Dimitrios Pappas MD, MPH

PROFESSIONAL EXPERIENCE
Oct. 2013 – Present
Director of Rheumatology, Division of Rheumatology, Athens Medical Center, Athens, Greece
Aug. 2013 – Present
Part-time Assistant Professor of Medicine, Columbia University School of Medicine, Department of Medicine, Division of Rheumatology, New York, NY
July 2009 – Present
Scientific Director, Consortium of Rheumatology Researchers of North America (CorEvitas), Waltham , MA
Nov. 2010 – Aug. 2013
Assistant Professor of Medicine, Columbia University School of Medicine, Department of Medicine, Division of Rheumatology, New York, NY
Nov. 2010- Aug. 2013
Director of Fast Arthritis Sonographic Evaluation and Treatment (FAST) Center, Department of Medicine, Division of Rheumatology, New York, NY
July 2010 – Nov. 2010
Assistant Professor of Medicine, Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, Baltimore MD
July 2009 – July 2010
Instructor of Medicine, Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, Baltimore MD
July 2009 – Nov. 2010
Co-Director, Rapid Arthritis Care and Evaluation ( RACE) Center, Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, Baltimore MD
 
Personal Data:
Greece:
Kifisias 56 & Delfon
Marousi, Athens
15125, Greece
Ph: +30 6948 230543
Fax: +30 210 8015315
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
United States:
Columbia University, College of Physicians and Surgeons
New York Presbyterian
P&S Building, Suite 10-455
New York, NY 10032
Ph: (212) 305-6192
Fax: (212) 304 6070
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Date of Birth: April 12th, 1974
Nationality: Greek
 
Education and Training
Undergraduate:
-
Not applicable for Greek educational system One-year studies in School of Biology, University of Iraklion, Creta, Greece
Doctoral/Graduate:
1999
M.D., Aristotle University of Thessaloniki, Thessaloniki, Greece
2009
Certification in Musculoskeletal Ultrasound for Rheumatologists, UltraSound School Of North America for Rheumatologists ( USSONAR), Philadelphia, USA
2012
MPH, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Postdoctoral:
1999-00
Social Service-Internship, General Hospital of Grevena, Grevena, Greece
(Obligatory for Medicine Graduates in Greece)
2001-02
Military service-Internship, Greek Army – Military Hospital of Xanthi, Xanthi, Greece. (Obligatory for Male Medicine Graduates in Greece)
2003
Internal Medicine Resident, Division of Internal Medicine, Hippokration University Hospital, Thessaloniki, Greece.
2003-06
Intern, Junior Resident, Senior Resident, Junior Chief Resident, Department of Medicine Albany Medical College – Union University, Albany, New York.
2006-09
Postdoctoral Fellow, Department of Medicine, Division of Rheumatology Johns Hopkins University School of Medicine, Baltimore, Maryland.
2008-12
Master of Public Health Student, Johns Hopkins School of Public Health, Baltimore, Maryland.
 
Professional experience
2009-10
Instructor of Medicine, Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
2010-10
Assistant Professor of Medicine, Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
2010- current
Assistant Professor of Medicine, Department of Medicine, Division of Rheumatology, Columbia University School of Medicine, New York, NY.
  • Until Aug 2013 as full time and since as part-time adjunct
 
RESEARCH ACTIVITIES
07/01/11-06/30/15
Inflammation and cardiovascular disease in rheumatoid arthritis
NIH/NIAMS
2R01 AR050026-07 ($2,059,071)
Bathon (PI), Institution: Columbia University
Total Direct Costs: 10% effort
Role: Co-investigator
07/01/09-06/30/14
Longitudinal Comparative effectiveness & Safety of Biologics in Autoimmunity (The CERTAIN study)
AHRQ
Curtis (PI), Institution: University of Alabama
RO1 RO1HS018517 ($2,393,997)
Role: Co-investigator

&

Consortium of Rheumatology Researchers of North America ( CORRONA)
Total Direct Costs: 50% effort
Role: Scientific Director for CERTAIN Study.
07/01/10-06/30/12
RA-associated Lung Disease: Using Quantitative Markers to Improve Clinical Practice
American College of Rheumatology Within Our Reach
Danoff (PI), Institution: Johns Hopkins
Total Direct Costs: 20% effort (relinquished upon leaving Johns Hopkins)
Role: Co- investigator
07/01/10-06/30/12
RA-associated Lung Disease: Using Quantitative Markers to Improve Clinical Practice
American College of Rheumatology Within Our Reach
Bathon (PI), Institution : Johns Hopkins
Total Direct costs: 20% effort
Role: Co-investigator (relinquished upon leaving Johns Hopkins)
07/01/07-06/30/10
The role of PAD4 in the pathogenesis of rheumatoid arthritis
MARRC Senior Fellowship
Arthritis Foundation, MD Chapter
Total Direct Costs: $150,000
Role: Principal Investigator
 
EDUCATIONAL ACTIVITIES
 
Peer-reviewed publications
  1. Pappas DA, Taube JM, Bathon JM, Giles JT. A 73-Year-Old Woman with Rheumatoid Arthritis and Shortness of Breath. Arthritis Rheum. 2008 Jun 15;59(6):892-9.
  2. Pappas DA, Giles JT. Do Anti-tumor Necrosis Factor Agents Increase the Risk of Postoperative Orthopedic Infections?. Curr Opin Rheumatol. 2008 Jul;20(4):450-6
  3. Pappas DA, Bathon JM, Hanicq D, Yasothan U, Kirkpatrick P. Golimumab. Nature Reviews Drug Discovery. 2009 Sep;8(9):695-6
  4. Pappas DA, Gelber CA. An emerging imitator. Am J Med. 2008 Nov;121(11):952-5.
  5. Pappas DA, Geraldino-Pardilla L, Bathon JM. Immune modulation of Rheumatoid Arthritis. Best Pract Res Clin Rheumatol. 2011 Dec;25(6):873-89.
  6. Pappas DA, Giles JT, Connors G, Wise RA, Lechtzin N, Bathon JM, Danoff SK. Respiratory symptoms and disease characteristics as predictors of pulmonary function abnormalities in patients with rheumatoid arthritis: an observational cohort study. Arthritis Res Ther. 2010 May 27;12(3):R104. 
  7. Giles JT, Fert-Bober J, Park JK, Bingham CO 3rd, Andrade F, Fox-Talbot K, Pappas D, Rosen A, van Eyk J, Bathon JM, Halushka MK. Myocardial citrullination in rheumatoid arthritis: A correlative histopathologic study Arthritis Res Ther. 2012 Feb 24;14(1):R39.
  8. Pappas DA, Oh C, Plenge R, Greenberg J. Association of Rheumatoid Arthritis Risk Alleles with Response to Anti-TNF Biologics: Results from the CORRONA Registry and Meta-analysis. Inflammation. 2013 Apr;36(2):279-84.
  9. McAllister K, Yarwood A, Bowes J, Orozco G, Viatte S, Diogo D, Hocking LJ, Steer S, Wordsworth P, Wilson AG, Morgan AW; UK Rheumatoid Arthritis Genetics Consortium; Rheumatoid Arthritis Consortium International, Kremer J, Pappas D, Gregersen P, Klareskog L, Plenge R, Barton A, Greenberg J, Worthington J, Eyre S. Meta-analysis identifies BACH2 and RAD51B as rheumatoid arthritis susceptibility loci. Arthritis Rheum. 2013 Sep 10. doi: 10.1002/art.38183. [Epub ahead of print].
  10. Navarro-Millán I, Chen L, Greenberg JD, Pappas DA, Curtis JR. Predictors and persistence of new-onset clinical remission in rheumatoid arthritis patients. Semin Arthritis Rheum. 2013 Oct;43(2):137-43.
  11. Okada Y, Wu D, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Robert R. Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC , Carroll RJ,. Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 2014 Feb 20;506(7488):376-81
  12. Okada Y, Diogo D, Greenberg JD, Mouassess F, Achkar WA, Fulton RS, Denny JC, Gupta N, Mirel D, Gabriel S, Li G, Kremer JM, Pappas DA, et al. Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. PLoS One. 2014 Feb 10;9(2):e87645.
  13. Pappas DA, Kremer JM, Reed G, Greenberg JD, Curtis JR. Design characteristics of the CORRONA CERTAIN study: a comparative effectiveness study of biologic agents for rheumatoid arthritis patients. BMC Musculoskelet Disord. 2014 Apr 1;15:113.
  14. Giles JT, Danoff SK, Sokolove J, Wagner CA, Winchester R, Pappas DA, Siegelman S, Connors G, Robinson WH, Bathon JM. Association of fine specificity and repertoire expansion of anticitrullinated peptide antibodies with rheumatoid arthritis associated interstitial lung disease. Ann Rheum Dis. 2014 Aug;73(8):1487-94.
  15. Yarwood A, Han B, Raychaudhuri S, Bowes J, Lunt M, Pappas DA, Kremer J, Greenberg JD, Plenge R; Rheumatoid Arthritis Consortium International (RACI), Worthington J, Barton A, Eyre S. A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk. Ann Rheum Dis. 2015 Jan;74(1):170-6.
  16. Kim K, Bang SY, Lee HS, Cho SK, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Kang YM, Kim SK, Suh CH, Shim SC, Lee SS, Lee J, Chung WT, Choe JY, Shin HD, Lee JY, Han BG, Nath SK, Eyre S, Bowes J, Pappas DA, et al. High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. Ann Rheum Dis. 2015 Mar;74(3):e13.
  17. Franke L, El Bannoudi H, Jansen DT, Kok K, Trynka G, Diogo D, Swertz M, Fransen K, Knevel R, Gutierrez-Achury J, Ärlestig L, Greenberg JD, Kremer J, Pappas DA, et al. Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes. Eur J Hum Genet. 2015 May 13.
  18. Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, et al. TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. PLoS One. 2015 Apr 7;10(4):e0122271.
  19. Pappas DA, Hooper MM, Kremer JM, Reed G, Shan Y, Wenkert D, Greenberg JD, Curtis JR. Herpes zoster reactivation in patients with rheumatoid arthritis: Analysis of disease characteristics and disease modifying anti-rheumatic drugs. Arthritis Care Res (Hoboken). 2015 May 27.
  20. Verstappen SM, Askling J, Berglind N, Franzen S, Frisell T, Garwood C, Greenberg JD, Holmqvist M, Horne L, Lampl K, Michaud K, Nyberg F, Pappas DA, Reed G, Symmons DP, Tanaka E, Tran TN, Yamanaka H, Ho M. Methodological challenges when comparing demographic and clinical characteristics of international observational registries. Arthritis Care Res (Hoboken). 2015 Jul 20.
  21. Nyberg F, Askling J, Berglind N, Franzén S, Ho M, Holmqvist M, Horne L, Lampl K, Michaud K, Pappas DA, et al. Using epidemiological registry data to provide background rates as context for adverse events in a rheumatoid arthritis drug development program: a coordinated approach. Pharmacoepidemiol Drug Saf. 2015 Aug 25.
  22. Pappas DA, Kent JD, Greenberg JD, Mason MA, Kremer JM, Holt RJ. Delays in Initiation of Disease-Modifying Therapy in Rheumatoid Arthritis Patients: Data from a US-Based Registry. Rheumatol Ther. 2015 Dec;2(2):153-164
  23. Franke L, El Bannoudi H, Jansen DT, Kok K, Trynka G, Diogo D, Swertz M, Fransen K, Knevel R, Gutierrez-Achury J, Ärlestig L, Greenberg JD, Kremer J, Pappas DA, et al. Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes. Eur J Hum Genet. 2016 Feb;24(2):263-70.
  24. Askling J, Berglind N, Franzen S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Horne L, Inoue E, Michaud K, Nyberg F, Pappas DA, et al.How comparable are rates of malignancies in patients with rheumatoid arthritis across the world? A comparison of cancer rates, and means to optimise their comparability, in five RA registries. Ann Rheum Dis. 2015 Nov 30. pii: annrheumdis-2015-208105.
  25. Franke L, El Bannoudi H, Jansen DT, Kok K, Trynka G, Diogo D, Swertz M, Fransen K, Knevel R, Gutierrez-Achury J, Ärlestig L, Greenberg JD, Kremer J, Pappas DA, et al. Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes. Eur J Hum Genet. 2016 Feb;24(2):263-70.
  26. Michaud K, Berglind N, Franzén S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Horne L, Inoue E, Nyberg F, Pappas DA, Reed G, Symmons D, Tanaka E, Tran TN, Verstappen SM, Wesby-van Swaay E, Yamanaka H, Askling J. Can rheumatoid arthritis (RA) registries provide contextual safety data for modern RA clinical trials? The case for mortality and cardiovascular disease. Ann Rheum Dis. 2016 Feb 8. pii: annrheumdis-2015-208698. doi: 10.1136/annrheumdis-2015-208698. [Epub ahead of print]
  27. Harrold LR, Reed GW, Kremer JM, Curtis JR, Solomon DH, Hochberg MC, Kavanaugh A, Saunders KC, Shan Y, Spruill TM, Pappas DA, Greenberg JD. Identifying factors associated with concordance with the American College of Rheumatology rheumatoid arthritis treatment recommendations. Arthritis Res Ther. 2016 Apr 26;18:94
  28. Curtis JR, Bharat A, Chen L, Greenberg JD, Harrold L, Kremer JM, Sommers T, Pappas D. Agreement between Rheumatologist and Patient-reported Adherence to Methotrexate in a US Rheumatoid Arthritis Registry.J Rheumatol. 2016 Jun;43(6):1027-9. doi: 10.3899/jrheum.151136. Epub 2016 May 1.
  29. Cui J, Diogo D, Stahl EA, Canhao H, Mariette X, Greenberg JD, Okada Y, Pappas DA, Fulton RS, Tak PP, Nurmohamed MT, Lee A, Larson DE, Kurreeman F, Deluca TL, O'Laughlin M, Fronick CC, Fulton LL, Mardis ER, van der Horst-Bruinsma IE, Wolbink GJ, Gregersen PK, Kremer JM, Crusius JB, de Vries N, Huizinga TW, Fonseca JE, Miceli-Richard C, Karlson EW, Coenen MJ, Barton A, Plenge RM, Raychaudhuri S. The role of rare protein-coding variants to anti-TNF treatment response in rheumatoid arthritis. Arthritis Rheumatol. 2016 Oct 27. doi: 10.1002/art.39966. [Epub ahead of print]
  30. Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, et al. Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nat Commun. 2016 Aug 23;7:12460. doi: 10.1038/ncomms12460.
  31. Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, et al. Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nat Commun. 2016 Oct 10;7:13205. doi: 10.1038/ncomms13205.
  32. Pappas DA, John A, Curtis JR, Reed GW, Karki C, Magner R, Kremer JM, Shewade A, Greenberg JD. Dosing of Intravenous Tocilizumab in a Real-World Setting of Rheumatoid Arthritis: Analyses from the Corrona Registry. Rheumatol Ther. 2016 Jun;3(1):103-115
  33. Reed GW, Collier DH, Koenig AS, Saunders KC, Pappas DA, Litman HJ, Kremer JM, Kotak S. Clinical and demographic factors associated with change and maintenance of disease severity in a large registry of patients with rheumatoid arthritis. Arthritis Res Ther. 2017 Apr 27;19(1):81. doi: 10.1186/s13075-017-1289-x.
  34. Yamanaka H, Kishimoto M, Pappas DA, Greenberg JD, Kremer JM, Tanaka Y.Design characteristics of the Corrona Japan rheumatoid arthritis registry. Mod Rheumatol. 2017 Apr 27:1-6. doi: 10.1080/14397595.2017.1317383. [Epub ahead of print]
  35. Yamanaka H, Askling J, Berglind N, Franzen S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Novelli Horne L, Inoue E, Michaud K, Pappas DA, Reed G, Symmons D, Tanaka E, Tran TN, Verstappen SMM, Wesby-van Swaay E, Nyberg F. Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme. RMD Open. 2017 Oct 10;3(2):e000498. doi: 10.1136/rmdopen-2017-000498. eCollection 2017.
  36. Pappas DA, Kremer JM, Griffith J, Reed G, Salim B, Karki C, Garg V.Long-Term Effectiveness of Adalimumab in Patients with Rheumatoid Arthritis: An Observational Analysis from the Corrona Rheumatoid Arthritis Registry. Rheumatol Ther. 2017 Dec;4(2):375-389. doi: 10.1007/s40744-017-0077-z. Epub 2017 Aug 24.
  37. Pappas DA, Nyberg F, Kremer JM, Lampl K, Reed GW, Horne L, Ho M, Onofrei A, Malaviya AN, Rillo OL, Radominski SC, Gal J, Gibofsky A, Popkova TV, Laurindo L, Kerzberg EM, Zahora R, Pons-Estel BA, Curtis JR, Furst DE, Greenberg JD. Prevalence of cardiovascular disease and major risk factors in patients with rheumatoid arthritis: a multinational cross-sectional study. Clin Rheumatol. 2018 Apr 25. doi: 10.1007/s10067-018-4113-3. [Epub ahead of print]
  38. Pappas DA, Gerber RA, Litman HJ, Gruben D, Geier J, Hua WD, Chen C, Li Y, Kremer JM, Andrews JS, Bourret JA. Delayed Treatment Acceleration in Patients with Rheumatoid Arthritis Who Have Inadequate Response to Initial Tumor Necrosis Factor Inhibitors: Data from the Corrona Registry. Am Health Drug Benefits. 2018 May;11(3):148-158.
  39. Curtis JR, Flake DD 2nd, Weinblatt ME, Shadick NA, Østergaard M, Hetland ML, Brahe CH, Hwang YG, Furst DE, Strand V, Etzel CJ, Pappas DA, Wang X, Hwang CC, Sasso EH, Gutin A, Hitraya E, Lanchbury JS. Adjustment of the multi-biomarker disease activity score to account for age, sex and adiposity in patients with rheumatoid arthritis. Rheumatology (Oxford). 2018 Dec 24. doi: 10.1093/rheumatology/key367. [Epub ahead of print]
  40. Lillegraven S, Greenberg JD, Reed GW, Saunders K, Curtis JR, Harrold L, Hochberg MC, Pappas DA, Kremer JM, Solomon DH.Immunosuppressive treatment and the risk of diabetes in rheumatoid arthritis. PLoS One. 2019 Jan 23;14(1):e0210459. doi: 10.1371/journal.pone.0210459. eCollection 2019.
  41. Pappas DA, Rebello S, Liu M, Schenfeld J, Li Y, Collier DH, Accortt NA.Therapy With Biologic Agents After Diagnosis of Solid Malignancies: Results From the Corrona Registry. J Rheumatol. 2019 Apr 1. pii: jrheum.171457. doi: 10.3899/jrheum.171457. [Epub ahead of print]
  42. Pappas DA, Etzel CJ, Zlotnick S, Best J, Blachley T, Kremer JM. Patterns of Prednisone Use in Patients with Rheumatoid Arthritis Initiating Treatment with Tocilizumab in Routine US Clinical Practice. Rheumatol Ther. 2019 Sep;6(3):421-433.
  43. Guan Y, Zhang H, Quang D, Wang Z, Parker SCJ, Pappas DA, Kremer JM, Zhu F. Machine Learning to Predict Anti-Tumor Necrosis Factor Drug Responses of Rheumatoid Arthritis Patients by Integrating Clinical and Genetic Markers. Arthritis Rheumatol. 2019 Dec;71(12):1987-1996.
  44. Farutin V, Prod'homme T, McConnell K, Washburn N, Halvey P, Etzel CJ, Guess J, Duffner J, Getchell K, Meccariello R, Gutierrez B, Honan C, Zhao G, Cilfone NA, Gunay NS, Hillson JL, DeLuca DS, Saunders KC, Pappas DA, Greenberg JD, Kremer JM, Manning AM, Ling LE, Capila I. Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor. Arthritis Res Ther. 2019 Oct 23;21(1):216.
  45. Pappas DA, Etzel CJ, Crabtree M, Blachley T, Best J, Zlotnick S, Kremer JM. Effectiveness of Tocilizumab in Patients With Rheumatoid Arthritis is Unaffected by Comorbidity Burden or Obesity: Data From a US Registry. J Rheumatol. 2020 Jan 15:jrheum.190282. doi: 10.3899/jrheum.190282. Online ahead of print.
  46. Pappas DA, Blachley T, Zlotnick S, Best J, Emeanuru K, Kremer JM. Methotrexate Discontinuation and Dose Decreases After Therapy With Tocilizumab: Results From the Corrona Rheumatoid Arthritis Registry. Rheumatol Ther. 2020 Jun;7(2):357-369.
  47. Curtis JR, Palmer JL, Reed GW, Greenberg J, Pappas DA, Harrold LR, Kremer JM. Real-World Outcomes Associated with Triple Therapy versus TNFi/MTX Therapy. Arthritis Care Res (Hoboken). 2020 May 6. doi: 10.1002/acr.24253. Online ahead of print.
  48. Pappas DA, St John G, Etzel CJ, Fiore S, Blachley T, Kimura T, Punekar R, Emeanuru K, Choi J, Boklage S, Kremer JM. Comparative effectiveness of first-line tumour necrosis factor inhibitor versus non-tumour necrosis factor inhibitor biologics and targeted synthetic agents in patients with rheumatoid arthritis: results from a large US registry study. Ann Rheum Dis. 2021 Jan;80(1):96-102. doi: 10.1136/annrheumdis-2020-217209. Epub 2020 Jul 21. PMID: 32719038.
  49. Bergman MJ, Kivitz AJ, Pappas DA, Kremer JM, Zhang L, Jeter A, Withers JB. Clinical Utility and Cost Savings in Predicting Inadequate Response to Anti-TNF Therapies in Rheumatoid Arthritis. Rheumatol Ther. 2020 Dec;7(4):775-792. doi: 10.1007/s40744-020-00226-3. Epub 2020 Aug 14. PMID: 32797404.
  50. Pappas DA, Litman HJ, Lesperance T, Kricorian G, Karis E, Rebello S, Hua W, Accortt NA, Stryker S. Persistence on biologic DMARD monotherapy after achieving rheumatoid arthritis disease control on combination therapy: retrospective analysis of corrona registry data. Rheumatol Int. 2021 Feb;41(2):381-390. doi: 10.1007/s00296-020-04667-5. Epub 2020 Sep 2. PMID: 32876744.
  51. Pappas DA, Shan Y, Lesperance T, Kricorian G, Karis E, Rebello S, Hua W, Accortt NA, Stryker S. Maintenance of Sustained Low Disease Activity or Remission in Patients With Rheumatoid Arthritis Treated With Etanercept Monotherapy: Results from the Corrona Registry. ACR Open Rheumatol. 2020 Oct;2(10):588-594. doi: 10.1002/acr2.11168. Epub 2020 Sep 29. PMID: 32990361.
  52. Winthrop KL, Citera G, Gold D, Henrohn D, Connell CA, Shapiro AB, Shi H, Onofrei AM, Pappas DA, Schulze-Koops H. Age-based (<65 vs ≥65 years) incidence of infections and serious infections with tofacitinib versus biological DMARDs in rheumatoid arthritis clinical trials and the US Corrona RA registry. Ann Rheum Dis. 2021 Jan;80(1):134-136. doi: 10.1136/annrheumdis-2020-218992. Epub 2020 Oct 12. PMID: 33046447. No abstract available.
  53. Kremer JM, Reed G, Pappas DA, Harold LR, Kane K, Greenberg J, Winthrop K. Hydroxychloroquine and the risk of respiratory infections among RA patients. RMD Open. 2020 Nov;6(3):e001389. doi: 10.1136/rmdopen-2020-001389. PMID: 33161375.
  54. Pappas DA, St John G, Etzel CJ, Fiore S, Blachley T, Kimura T, Punekar R, Emeanuru K, Choi J, Boklage S, Kremer JM. Response to 'Correspondence on 'Comparative effectiveness of first-line tumour necrosis factor inhibitor versus non-tumour necrosis factor inhibitor biologics and targeted synthetic agents in patients with rheumatoid arthritis: results from a large US registry study'' by Zheng et al. Ann Rheum Dis. 2020 Nov 11:annrheumdis-2020-218907. doi: 10.1136/annrheumdis-2020-218907. Online ahead of print. PMID: 33177102 No abstract available.
  55. Pappas DA, Brittle C, Mossell JE 3rd, Withers JB, Lim-Harashima J, Kremer JM. Perceived clinical utility of a test for predicting inadequate response to TNF inhibitor therapies in rheumatoid arthritis: results from a decision impact study. Rheumatol Int. 2021 Mar;41(3):585-593. doi: 10.1007/s00296-020-04746-7. Epub 2020 Nov 30. PMID: 33258003.
  56. Kremer JM, Pappas DA, Kane K, Greenberg J, Harrold L, Feathers VL, Shadick N, Weinblatt ME, Reed G. The Clinical Disease Activity Index (CDAI) and the Routine Assessment of Patient Index Data3 (RAPID3) for Achievement of Treatment Strategies. J Rheumatol. 2020 Dec 15:jrheum.200692. doi: 10.3899/jrheum.200692. Online ahead of print. PMID: 33323534.
  57. Petro AD, Dougherty J, England BR, Sayles H, Duryee MJ, Hunter CD, Kremer JM, Pappas DA, Robinson WH, Curtis JR, Thiele GM, Mikuls TR. Associations between an expanded autoantibody profile and treatment responses to biologic therapies in patients with rheumatoid arthritis. Int Immunopharmacol. 2021 Feb;91:107260. doi: 10.1016/j.intimp.2020.107260. Epub 2020 Dec 23. PMID: 33360371.
  58. Halvey P, Farutin V, Koppes L, Gunay NS, Pappas DA, Manning AM, Capila I. Variable blood processing procedures contribute to plasma proteomic variability. Clin Proteomics. 2021 Jan 19;18(1):5. doi: 10.1186/s12014-021-09311-3. PMID: 33468058.
  59. Kremer JM, Bingham CO 3rd, Cappelli LC, Greenberg JD, Madsen AM, Geier J, Rivas JL, Onofrei AM, Barr CJ, Pappas DA, Litman HJ, Dandreo KJ, Shapiro AB, Connell CA, Kavanaugh A. Postapproval Comparative Safety Study of Tofacitinib and Biological Disease-Modifying Antirheumatic Drugs: 5-Year Results from a United States-Based Rheumatoid Arthritis Registry. ACR Open Rheumatol. 2021 Feb 11. doi: 10.1002/acr2.11232. Online ahead of print.PMID: 33570260.
  60. Pappas DA, Blachley T, Best JH, Zlotnick S, Reiss WG, Emeanuru K, Kremer JM. Durability of Response to Tocilizumab Therapy in Rheumatoid Arthritis: Data from the US-Based Corrona Rheumatoid Arthritis Registry. Rheumatol Ther. 2021 Feb 25. doi: 10.1007/s40744-021-00285-0. Online ahead of print.PMID: 33630272.
  61. Harrold LR, Bryson J, Lehman T, Zhuo J, Gao S, Han X, Schrader A, Rebello S, Pappas DA, Sommers T, Kremer JM. Association Between Baseline Anti-cyclic Citrullinated Peptide Antibodies and 6-Month Clinical Response Following Abatacept or TNF Inhibitor Treatment: A Real-World Analysis of Biologic-Experienced Patients with RA. Rheumatol Ther. 2021 Jun;8(2):937-953. doi: 10.1007/s40744-021-00310-2. Epub 2021 May 28.PMID: 34047953.
  62. Ocon AJ, Reed G, Pappas DA, Curtis JR, Kremer JM.Short-term dose and duration-dependent glucocorticoid risk for cardiovascular events in glucocorticoid-naive patients with rheumatoid arthritis. Ann Rheum Dis. 2021 Jul 2:annrheumdis-2021-220577. doi: 10.1136/annrheumdis-2021-220577. Online ahead of print.PMID: 34215644.
  63. Cohen S, Wells AF, Curtis JR, Dhar R, Mellors T, Zhang L, Withers JB, Jones A, Ghiassian SD, Wang M, Connolly-Strong E, Rapisardo S, Gatalica Z, Pappas DA, Kremer JM, Saleh A, Akmaev VR.A Molecular Signature Response Classifier to Predict Inadequate Response to Tumor Necrosis Factor-α Inhibitors: The NETWORK-004 Prospective Observational Study. Rheumatol Ther. 2021 Sep;8(3):1159-1176. doi: 10.1007/s40744-021-00330-y. Epub 2021 Jun 19.PMID: 34148193.
 
Book Chapters, Monographs
  1. Pappas DA, Bathon JM. (2008). Treatment of Rheumatoid Arthritis: Tumor Necrosis Factor Inhibitors. In Hohcberg MC, Silman AJ, Smolen JS, Weniblatt ME, Weisman MH (Eds), Rheumatoid Arthritis (pp 337-349). Philadephia: Mosby
  2. Pappas DA. Musculoskeletal Ultrasound in Rheumatology. In Current Medical Diagnosis and Treatment ((Rheumatology), McGraw-Hill)) Third Edition, (pp 515-520). Lange
  3. Pappas DA, Kremer JM. Registry Design: Developing Prospective Nested Studies in Existing Registries. In Registries for Evaluating Patient Outcomes. Agency for Healthcare Research and Quality publication Third Edition
  4. Pappas DA, Bathon JM. Rheumatoid Arthritis: Extraarticular manifestations. In Mackay IR, Rose NR (Eds), Encyclopedia of Medical immunology. Springer
 
Case Reports
  1. Pappas DA. A young woman with cervical lymphadenopathy – A case report. Albany Medical Review 2004; www.amc.edu/Amr/archives/200411/case3.html
 
International meeting presentations
  1. Pappas DA. When vertigo turns out to be Sarcoidosis. American College of Physicians, 2005 Annual Scientific meeting, San Fransisco, California, April 2005
  2. Pappas DA, Pappa C, Kremer JM. Giant Cell Arteritis presenting as aortitis and subsequent aortic dissection. American College of Physicians, 2005 Annual New York Chapter Upstate Scientific Meeting, Rochester, New York, October 2005.
  3. Pappas DA, Rodriguez-Pla A, Bathon JM, Giles JT. Glucocorticoid Treatment is Associated with Increased Prevalence of Insulin Resistance In Subjects With Rheumatoid Arthritis. Arthritis and Rheumatism Abstract Supplement 2007; 56(9):S411. American College of Rheumatology National Meeting.
  4. Danoff SK, Pappas DA, Bathon JM. Prevalence Of PFT Abnormalities And Respiratory Symptoms In An RA Patient Cohort. American Thoracic Society, 2008 International Meeting, Toronto, Canada, May 2008.
  5. Pappas DA, Giles JT, Connors G, Lectzin N, Bathon JM, Danoff SK. Respiratory symptoms and disease characteristics as predictors of Pulmonary Function Abnormalities(PFT) in Patients with Rheumatoid Arthritis (RA). Arthritis and Rheumatism Abstract Supplement 2009; 60(10):S359 American College of Rheumatology National Meeting.
  6. Pappas, DA; Greenberg, JD; Stevens, C; Reed, G; Greenstein, N; Flaherty, L; Kremer, JM. Identification of a single nucleolide polymorphism in MIF gene associated with erosive radiographic damage in patients with rheumatoid arthritis. Arthritis Rheum 2005; 52: S146.
  7. Pappas, DA; Greenberg, JD; Stevens, C; Reed, G; Greenstein, N; Flaherty, L; Kremer, JM. Polymorphisms of the uteroglobin gene as a marker of disease activity in rheumatoid arthritis. Arthritis Rheum. 2005; 52: S120.
  8. Pappas, DA; Stevens, C; Greenberg, JD; Reed, G; Greenstein, N; Kremer, JM; Flaherty, L. Identification of single nucleotide polymorphisms in the Mmp3 and SCGB1A1 genes associated with RA susceptibility in a Caucasian population. Arthritis Rheum 2005; 52: S147
  9. Harrington JT, Pappas DA, Messing S, Tu X, Chen R, Kaukeinen K, Pietras T. Dosing of anti-tumor necrosis factor biologics (anti-TNFs) for rheumatoid arthritis (RA) and psoriatic arthritis (PsA) in Clinical Practice in the United States. Arthritis Rheum 2010;62(Suppl 10):1799.
  10. Pappas DA, Rathbun A, Reed G, Kremer JM, Villanueva I, Devenport J, Ogale S. A profile of rheumatoid arthritis patients treated with tocilizumab in a United States registry population. Arthritis Rheum 2011;63(Suppl 10):1262.
  11. Pappas DA, Hooper M, Reed G, Shan Y, Wenkert D, Zhang J, Greenberg J, Curtis J. Risk for herpes zoster after treatment with biologic and synthetic disease modifying agents for rheumatoid arthritis. Ann Rheum Dis 2012;71(Suppl 3):346.
  12. Pappas DA, John A, Greenberg JD, Devenport J, Kremer JM, Ogale S, Reed GW, Saunders KC, Curtis JR. Design characteristics of the CORRONA CERTAIN study: a US comparative effectiveness and biomarkers study of rheumatoid arthritis biologic agents. Ann Rheum Dis 2012;71(Suppl 3):668.
  13. Pala O, Messing S, Hopkins A, Reed G, Perez-Rivera M, Acosta M, Kremer JM, Lozada C, Pappas DA. Effect of alcohol on response to therapy with TNF-A inhibitors for rheumatoid arthritis: results from CORRONA registry. Ann Rheum Dis 2012;71(Suppl 3):369.
  14. Pala O, Messing S, Hopkins A, Reed G, Perez-Rivera M, Acosta M, Kremer JM, Lozada C, Pappas DA. Effect of smoking on response to therapy with the TNF-A inhibitors for Rheumatoid arthritis: results from the CORRONA registry. Ann Rheum Dis 2012;71(Suppl 3):521.
  15. Manno RL, Pappas DA, Saunders KC, Reed GW, Grant S, Bingham CO. Disease-modifying antirheumatic drug use among elderly with rheumatoid arthritis. Arthritis Rheum 2012;64(Suppl 10):2480.
  16. Pappas DA, Reed GW, John A, Shewade A, Saunders KC, Devenport J, Greenberg JD, Kremer JM. Predictors of initiating biologic monotherapy in biologic naïve patients with rheumatoid arthritis (RA) in a United States registry population. Arthritis Rheum 2012;64(Suppl 10):491.
  17. Pappas DA, Reed GW, Saunders KC, John A, Shewade A, Devenport J, Greenberg JD, Kremer JM. Characteristics associated with biologic initiation as monotherapy versus combination Therapy in patients with rheumatoid arthritis (RA) in a United States registry population. Arthritis Rheum 2012;64(Suppl 10):557.
  18. Pappas DA, Lampl K, Kremer JM, Nyberg F, Gibofsky A, Ho M, Horne L, Saunders K, Onofrei AU, Greenberg JD. The CORRONA international rheumatoid arthritis registry: variations in disease activity and management across participating regions. Ann Rheum Dis 2013;72(Suppl 3):209.
  19. Pappas DA, John A, Curtis JR, Kremer J, Reiss W, Shewade A, Silverman GJ, Greenberg JD. Prevalence of low immunoglobulin levels and associations with rheumatoid arthritis factors. Ann Rheum Dis 2013;72(Suppl 3):448.
  20. Pappas DA, John A, Kremer J, Reed G, Greenberg JD, Shewade A, Solomon DH, Curtis JR. Effect of biologic agents on lipids and cardiovascular risk in rheumatoid arthritis patients. Ann Rheum Dis 2013;72(Suppl 3):49.
  21. Lillegraven S, Greenberg JD, Reed GW, Saunders K, Curtis JR, Harrold L, Hochberg M, Pappas D, Kremer JM, Solomon DH. Use of TNF inhibitors is associated with a reduced risk of diabetes in RA patients. Ann Rheum Dis 2013;72(Suppl 3):106.
  22. Pappas DA, Kremer J, Greenberg J, Shewade A., Solomon D, Curtis JR. Dyslipidemia, inflammation and cardiovascular risk in patients with rheumatoid arthritis. International Conference on Pharmacoepidemiology and Therapeutic Risk Management 25-28 August 2013. Montreal, Canada.
  23. Yamanaka H, Askling J, Berglind N, Franzén S, Frisell T, Garwood C. Greenberg JD, Ho M, Holmqvist M, Horne L, Inoue E, Lampl K, Michaud K, Pappas DA, Reed G, Symmons D, Tanaka E, Tran T, Verstappen S, Nyberg F. Rates of hospitalized infections in rheumatoid arthritis patients from 5 rheumatoid arthritis registries across the world. Arthritis Rheum 2013;65(Suppl 10):1047.
  24. Pappas DA, Lampl K, Kremer JM, Radominski SC, Gal J, Nyberg F, Malaviya A, Whitworth A, Rillo O, Gibofsky A, Popkova T, Ho M, Laurindo I, Reed GW, Kerzberg E, Horne L, Zahora R, Saunders K , Pons-Estel B, Onofrei AU , Greenberg JD. Variations in disease activity and therapeutic management of RA in different international regions. Data from the CORRONA International and CORRONA US registries. Arthritis Rheum 2013;65(Suppl 10):1303.
  25. Pappas DA, Chen L, Harrold LR, Reed G, Kremer J, Greenberg JD, Curtis JR. Physician variability in rheumatoid patients not receiving biologics or non-biologic DMARDs: implications for quality reporting. Arthritis Rheum 2013;65(Suppl 10):193.
  26. Pappas DA, John A, Curtis JR, Reed GW, Sommers T, Greenberg JD, Shewade A, Solomon DH, Kremer JM. Effect of biologic agents on lipids and cardiovascular risk in rheumatoid arthritis patients. Arthritis Rheum 2013;65(Suppl 10):2827.
  27. Pappas DA, John A, Curtis JR, Reed GW, Sommers T, Greenberg JD, Shewade A, Kremer JM. Shift in cardiovascular risk and lipid levels in rheumatoid arthritis using ATP-3 guidelines: CORRONA CERTAIN study. Arthritis Rheum 2013;65(Suppl 10):370.
  28. Pappas DA, John A, Kremer JM, Karki CK, Sommers T, Reed GW, Curtis JR, Shewade A, Greenberg JD. Effect of tocilizumab on treatment patterns, effectiveness and safety with laboratory values for patients with rheumatoid arthritis: analyses from the CORRONA – CERTAIN Study. Arthritis Rheum 2013;65(Suppl 10):2344.
  29. Pappas DA, John A, Kremer JM, Reed GW, Sommers T, Greenberg JD, Shewade A, Curtis JR. Management of hyperlipidemia in patients with rheumatoid arthritis: results from the CORRONA CERTAIN study. Arthritis Rheum 2013;65(Suppl 10):362.
  30. Pappas DA, Karki CK, Lee C, Reed GW, He P, Al Sawah S. Patient reported pain: a predictor of outcomes in rheumatoid arthritis from the Consortium of Rheumatology Researchers of North America (CORRONA) registry. Arthritis Rheum 2013;65(Suppl 10):2269.
  31. Pappas DA, Lampl K, Kremer JM, Radominski SC, Gal J, Nyberg F, Malaviya A, Whitworth A, Rillo O, Gibofsky A, Popkova T, Ho M, Laurindo I, Reed GW, Kerzberg E, Horne L, Zahora R, Saunders K , Pons-Estel B, Onofrei AU , Greenberg JD. Prevalence of cardiovascular risk factors and cardiovascular disease in different international regions. Data from the CORRONA International and CORRONA US registries. Arthritis Rheum 2013;65(Suppl 10):392.
  32. Lillegraven S, Greenberg JD, Reed GW, Saunders K, Curtis JR, Harrold LR, Hochberg MC, Pappas DA, Kremer JM, Solomon DH. Use of TNF inhibitors is associated with a reduced risk of diabetes in RA patients. Arthritis Rheum 2013;65(Suppl 10):1040.
  33. Hopkins A, Martinez-Marti A, Reed G, He P, Greenberg JD, Lozada C, Pala O, Kremer JM, Pappas DA. Effectiveness of TNF-á inhibitor therapy does not differ between elderly and younger patients with rheumatoid arthritis: results from the CORRONA registry. Arthritis Rheum 2013;65(Suppl 10):1435.
  34. Dimitrios Pappas, Carol Etzel, Angela Bedenbaugh, Jeymi Tambiah, Jeff Greenberg. Baseline characteristics of elderly RA patients treated with Certolizumab Pegol and other TNF-a inhibitors. Results from the CORRONA registry. International Society For Pharmacoeconomics and Outcomes Research. Montreal, Canada. 31, May – 4 June 2014.
  35. Pappas DA, John A, Reed GW, Karki C, Greenberg JD, Shewade A, Kremer JM. Persistency and its predictors of biologic monotherapy in patients with RA: analyses from the CORRONA RA registry. Ann Rheum Dis 2014;73(Suppl2):496-497.
  36. Pappas DA, Lampl K, Kremer JM, Radominski SC, Gal J, Nyberg F, Malaviya A, Whitworth A, Rillo O, Gibofsky A, Popkova T, Ho M, Laurindo I, Reed GW, Kerzberg E, Horne L, Zahora R, Saunders K , Pons-Estel B, Onofrei AU , Greenberg JD. Prevalence of cardiovascular risk factors and cardiovascular disease in rheumatoid arthritis patients across international regions: a comparison of the CORRONA International and CORRRONA US registries. Ann Rheum Dis 2014;73(Suppl2):639.
  37. Pappas DA, Lampl K, Kremer JM, Radominski SC, Gal J, Nyberg F, Malaviya A, Whitworth A, Rillo O, Gibofsky A, Popkova T, Ho M, Laurindo I, Reed GW, Kerzberg E, Horne L, Zahora R, Saunders K , Pons-Estel B, Onofrei AU , Greenberg JD. Variations in disease activity and therapeutic management of rheumatoid arthritis in different international regions: a comparison of data from the CORRONA International and CORRONA RA registries. Ann Rheum Dis 2014;73(Suppl2):400.
  38. Pappas DA, Shaw J, Chang H, Cifaldi M, Reed GW, Garg V, Lacerda A, Mozaffarian N. Laboratory safety of adalimumab and other tumor necrosis factor inhibitors in the treatment of rheumatoid arthritis. Ann Rheum Dis 2014;73(Suppl2):931.
  39. Pappas DA, John A, Curtis JR, Reed GW, Karki C, Magner R, Kremer JM, Shewade A, Greenberg JD. Dosing of intravenous tocilizumab in a real-world setting—analyses from a US RA registry. Arthritis Rheum 2014;66(Suppl11):515.
  40. Pappas DA, Kent JD, Kremer JM, Mason M, Grahn AY, Greenberg JD, Holt RJ. Characteristics of rheumatoid arthritis patients not receiving early initiation of disease modifying therapy. Arthritis Rheum 2014;66(Suppl11):2415.
  41. Curtis JR, Bharat A, Chen L, Greenberg JD, Kremer J, Pappas D. Physician awareness of suboptimal patient adherence to MTX: results from a large U.S. rheumatoid arthritis registry. Arthritis Rheum 2014;66(Suppl11):2367.
  42. Pappas DA, John A, Curtis JR, Etzel CE, Karki C, Ssemakula J, Kremer JM, Shewade A, Greenberg JD. Patterns of biologic discontinuations within the Corrona registry: CERTAIN study. Ann Rheum Dis2015;74(Suppl2):1044.
  43. Pappas D, Reed GW, Bao Y, Grant SP, Garg V. Impact of biologic discontinuation in patients with rheumatoid arthritis: observation from the Corrona registry. Ann Rheum Dis2015;74(Suppl2):226.
  44. Pappas DA, Griffith J, Karki C, Liu M, Kremer JM, Ganguli A, Greenberg JD. The Impact of Biologic Agent Initiation after 1 Versus 2 Prior Csdmards in Patients with Rheumatoid Arthritis. Arthritis Rheumatol. 2015; 67 (suppl 10).
  45. Pappas DA, Holt RJ, Shan Y, Kent JD, Nguyen JT, Kremer JM, Greenberg JD. The Influence of Patient Reported Morning Stiffness on Patient Global Assessment in Rheumatoid Arthritis Patients Not Achieving ACR/EULAR Boolean Remission in a Large US Registry. Arthritis Rheumatol. 2015; 67 (suppl 10).
  46. Pappas DA, John A, Etzel CJ, Karki C, Li Y, Kremer JM, Haselkorn T, Greenberg JD. Persistency of Tocilizumab As Monotherapy or Combination Therapy in Patients with Rheumatoid Arthritis–Real-World Analyses from the US Corrona Registry. Arthritis Rheumatol. 2015; 67 (suppl 10).
  47. Pappas DA, Karki C, Liu M, Kremer JM, Greenberg JD, Garg V. Delay in initiation of biologics among bio-eligible patients with rheumatoid arthritis in US: Evidence from the Corrona registry. Ann Rheum Dis2016;75(Suppl2): 248.
  48. Pappas DA, John A, Kremer JM, Reed GW, Sommers T, Greenberg JD, Curtis JR. Comparative Effectiveness of Biologic Agents for Patients with Rheumatoid Arthritis—Primary Analysis from the US Corrona CERTAIN Study. Ann Rheum Dis2016;75(Suppl2): 1020.
  49. Pappas DA, Karki C, Litman HJ, Greenberg JD, Garg V, Kremer JM. Need to advance therapy in rheumatoid arthritis patients treated with triple nbDMARD vs biologic combination therapy: Results from the Corrona registry. Ann Rheum Dis2016;75(Suppl2): 249
  50. Harrold LR, Palmer JL, Pappas DA, Kremer JM, Greenberg JD. Trends in the achievement of low disease activity among a US National sample of RA pts initiating biologics. Ann Rheum Dis2016;75(Suppl2): 199.
  51. Pappas DA, Griffith J, Litman HJ, Schlacher CA, Salim BA, Karki C, Kremer JM. Time to Initiation of Biologic Agents Is Associated with Glucocorticoid Use: Results from the Corrona Registry [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10).
  52. Pappas DA, Rebello S, Liu M, Schenfeld J, Li Y, Collier DH, Accortt N. Therapy with Biologic Agents after Diagnosis of Solid Malignancies; Results from the Corrona Registry [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10).
  53. Pappas DA, Griffith J, Schlacher C, Shan Y, Karki C, Kremer JM. Effectiveness of Low and High Dose Methotrexate in Combination with Adalimumab in a Real World Setting: Results from the Corrona Rheumatoid Arthritis Registry. Ann Rheum Dis2017;76(Suppl2): 827. Poster
  54. Pappas DA, Griffith J, Schlacher C, Suboticki JL, Harrison R, Shan Y, Karki C, Kremer JM. Effectiveness of Adalimumab Combination Therapy with Methotrexate and Non-Methotrexate csDMARDs: Results from the Corrona Rheumatoid Arthritis Registry. Ann Rheum Dis2017;76(Suppl2): 552. Poster
  55. Pappas DA, Reed GW, Zlotnick S, Best J, Magner R, Persuitte G, Greenberg JD. Repeated Rituximab Infusions for the Therapy of Rheumatoid Arthritis is not Associated with Increased Rates of Serious Infections. Ann Rheum Dis2017;76(Suppl2): 846. Poster
  56. Pappas DA, Sasso EH, Bolce RJ, Liu X, Etzel CJ. The Multi-Biomarker Disease Activity (MBDA) Score for Assessing Response to Treatment with Adalimumab. Ann Rheum Dis2017;76(Suppl2): 1121. Publication
  57. Pappas DA, Etzel CJ, Best J, Zlotnick S, Blachley T, Persuitte G, Kremer JM. Patterns of Prednisone Use in US Patients With Rheumatoid Arthritis Initiating Treatment With Tocilizumab in Routine Clinical Practice. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  58. Pappas DA, Karki C, Litman HJ, Blachley T, Suboticki JL, Griffith J, Kremer JM. Impact of Adalimumab on Prednisone Use in Patients with Rheumatoid Arthritis in a Real World Setting – Results from Corrona Registry. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  59. Pappas DA, Karki C, Shan Y, Suboticki JL, Griffith J, Kremer JM. Methotrexate Discontinuation from Combination Therapy with Adalimumab is not Associated with Inferior Outcomes at 6 Months. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  60. Pappas DA, Murray J, Etzel CJ, Nelson D, Gershenson B, Saunders KC, Rebello S, Kremer JM. Rheumatoid Arthritis Patient Characteristics Also Predict Response to Therapy with Biologic Agents: Results from the Corrona CERTAIN Study. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  61. Pappas DA, Reed GW, Karki C, Griffith J, Skup M, Garg V, Kremer J. Real-world Consistency of Response to Adalimumab Over Time in Patients With Rheumatoid Arthritis: Results From the Corrona Registry. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  62. Pappas DA, Reed GW, Zlotnick S, Best J, Magner R, Persuitte G, Greenberg JD. Repeated Rituximab Infusions for the Therapy of Rheumatoid Arthritis Is Not Associated With Increased Rates of Serious Infections. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  63. Farutin V, Prod’homme T, McConnell K, Halvey P, Washburn N, Cilfone N, Kyriakis S, Hillson J, Etzel CJ, Saunders KC, Pappas DA, Manning A, Ling L, Capila I. Molecular Profiling of RA Patients Suggests a Differential Involvement of Adaptive and Innate Cell Populations in Response to Anti-TNF Treatment. Arthritis Rheumatol. 2017; 69 (suppl 10). Poster
  64. Pappas DA, Etzel CJ, Crabtree M, Best J, Zlotnick S, Kremer JM. Impact of Comorbidity Burden and Obesity on the Effectiveness of Tocilizumab in Patients with Rheumatoid Arthritis. Ann Rheum Dis2018;**(Suppl*): *** .Poster
  65. Pappas DA, Litman HJ, Lesperance T, Rebello S, Karis E, Kricorian G, Hua D, Accortt NA. Persistence on Tumor Necrosis Factor Inhibitor (TNFi) Monotherapy Among Patients with Rheumatoid Arthritis (RA) in Remission or Low Disease Activity (LDA). Ann Rheum Dis2018;77(Suppl): A600 .Poster
  66. Pappas DA, Saunders KC, Etzel CJ, Hua DW, Deering K, Zueger P, Garg V. Evaluation of the Use of Ultrasound to Manage Patients With Rheumatoid Arthritis Over Time: Results From the Corrona Registry. Ann Rheum Dis2018;77(Suppl): A906 .Poster
  67. Pappas DA, Etzel CJ, Crabtree M, Best JH, Zlotnick S, Kremer J. Impact of Comorbidity Burden and Obesity on the Effectiveness of Tocilizumab in Patients with Rheumatoid Arthritis [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). Poster
  68. Pappas DA, Shan Y, Lesperance T, Rebello S, Karis E, Kricorian G, Hua W, Accortt NA, Stryker S. Persistence in Low Disease Activity or Remission with Etanercept Monotherapy in Patients with Rheumatoid Arthritis: Results from the Corrona Registry [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). Poster
  69. Pappas DA, St. John G, Etzel CJ, Fiore S, Blachley T, Kimura T, Punekar R, Emeanuru K, Boklage S, Kremer J. The Comparative Effectiveness of First-Line Tumor Necrosis Factor Inhibitor (TNFi) Compared with Non-TNFi Agents in Patients with Rheumatoid Arthritis: Results from the Corrona Registry [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10).
  70. Pappas DA, Tundia N, Shan Y, Litman HJ, Kremer J. Unmet Treat-to-Target Goals with Available Targeted Immunomodulators in the Management of Rheumatoid Arthritis: Real World Evidence from the Corrona Registry [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). Poster
  71. Mikuls TR, Bath A, England BR, Duryee MJ, Hunter CD, Kremer J, Pappas DA, Robinson WH, Curtis JR, Thiele GM. Expanded Autoantibody Profiles Predict Treatment Response to Biologic Therapy in Rheumatoid Arthritis [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10).
  72. Curtis JR, Palmer JL, Reed GW, Greenberg J, Pappas DA, Harrold LR, Kremer J. Real-World Outcomes Associated with Triple Therapy Vs. TNFi Combo Therapy: Results from the Corrona Registry [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10).
  73. Pappas DA, Blachley T, Zlotnick S, Best J, Emeanuru K, Kremer JM. Methotrexate Discontinuation and Dose Decreases After Therapy With Tocilizumab: Results From the Corrona Rheumatoid Arthritis Registry. Ann Rheum Dis, volume 78, supplement 2, year 2019, page A1150. Poster
  74. Kremer J, Bingham C, Cappelli L, Etzel C, Greenberg J, Geier J, Madsen A, Chen C, Onofrei A, Barr C, Pappas DA, Litman HJ, Dandreo KJ, Shapiro A, Connell CA, Kavanaugh A. Post-Approval Comparative Safety Study Of Tofacitinib And Biologic Dmards: Five Year Results From A Us-Based Rheumatoid Arthritis Registry. Ann Rheum Dis, volume 78, supplement 2, year 2019, page A82. Presentation
  75. Pappas D, Blachley T, Zlotnick S, Best J, Emeanuru K, Kremer J. Methotrexate Discontinuation and Dose Decreases After Therapy with Tocilizumab: Results from the Corrona Rheumatoid Arthritis Registry [abstract]. Arthritis Rheumatol. 2019; 71 (suppl 10).
  76. Pappas D, Blachley T, Zlotnick S, Best J, Emeanuru K, Kremer J. Comparative Effectiveness of Tocilizumab in Combination with Methotrexate versus Tumor Necrosis Factor Inhibitors (TNFis) in Combination with Methotrexate in Patients with Rheumatoid Arthritis with Prior Exposure to TNFis [abstract]. Arthritis Rheumatol. 2019; 71 (suppl 10).
  77. Pappas D, Blachley T, Best J, Zlotnick S, Emeanuru K, Kremer J. Persistence of Tocilizumab Therapy Among Patients with Rheumatoid Arthritis: Data from the US-Based Corrona Rheumatoid Arthritis Registry [abstract]. Arthritis Rheumatol. 2019; 71 (suppl 10).
  78. Kremer J, Bingham C, Cappelli L, Greenberg J, Geier J, Madsen A, Chen C, Onofrei A, Barr C, Pappas D, Litman H, Dandreo K, Shapiro A, Connell C, Kavanaugh A. Post-Approval Comparative Safety Study of Tofacitinib and Biologic DMARDs: Five‑Year Results from a US-based Rheumatoid Arthritis Registry [abstract]. Arthritis Rheumatol. 2019; 71 (suppl 10).
  79. Kremer J, Bingham C, Cappelli L, Greenberg J, Madsen A, Geier J, Rivas J, Onofrei A, Barr C, Pappas D, Litman H, Dandreo K, Shapiro A, Connell C, Kavanaugh A. Comparison of Malignancy and Mortality Rates Between Tofacitinib and Biologic DMARDs in Clinical Practice: Five-Year Results from a US-Based Rheumatoid Arthritis Registry [abstract]. Arthritis Rheumatol. 2019; 71 (suppl 10).
  80. Pappas DA, Blachley T, Zlotnick S, Best J, Emeanuru K, Kremer JM. Comparative Effectiveness of Tocilizumab in Combination With Methotrexate Versus Tumor Necrosis Factor Inhibitors (TNFis) in Combination With Methotrexate in Patients With Rheumatoid Arthritis With Prior Exposure to TNFis. June 2020 Volume 79 Supplement 1. DOI: 10.1136/annrheumdis-2020-eular.588. Poster
  81. Pappas DA, Blachley T, Best J, Zlotnick S, Emeanuru K, Kremer JM. Persistence of Tocilizumab Therapy Among Patients With Rheumatoid Arthritis: Data From the US-Based Corrona Rheumatoid Arthritis Registry. June 2020 Volume 79 Supplement 1. DOI: 10.1136/annrheumdis-2020-eular.708. Poster
  82. Pappas DA, Blachley T, Best J, Zlotnick S, Reiss W, Emeanuru K, Kremer JM. Durability of Response Among Patients With Rheumatoid Arthritis Initiating Tocilizumab: Data From the US-Based Corrona Rheumatoid Arthritis Registry. June 2020 Volume 79 Supplement 1. DOI: 10.1136/annrheumdis-2020-eular.571. Poster
 
Other media (films, videos, CD-ROMs, slide sets, etc)
  1. Ask the expert educational videos. The Johns Hopkins Arthritis Center Website.Pappas DA, Ruffing V. Ultrasound and Rheumatoid Arthritis. http://www.hopkins-arthritis.org/ask-the-expert/video/
  2. Ask the expert educational videos. The Johns Hopkins Arthritis Center Website:Pappas DA, Ruffing V. Symptoms of Rheumatoid Arthritis. http://www.hopkins-arthritis.org/ask-the-expert/video/
  3. Ask the expert educational videos. The Johns Hopkins Arthritis Center Website:Pappas DA, Ruffing V. How to locate a rheumatologist. http://www.hopkins-arthritis.org/ask-the-expert/video/
  4. WEBMD:Pappas DA. Biologic treatment in Rheumatoid Arthritis. Ask the expert video. http://www.webmd.com/rheumatoid-arthritis/biologics-10/choosing-biologics-video
  5. CBS television broadcast: Musculoskeletal Ultrasound in Rheumatology: Pappas DA
    CBS new York: http://newyork.cbslocal.com/video/7031241-dr-max-gomez-arthritis-ultrasounds/
    CBS Pitssburgh: http://pittsburgh.cbslocal.com/2012/04/20/ultrasound-offering-arthritis-patients-some-relief/
    *this story was broadcasted in several states by CBS
  6. CBS Radio Broadcast: The Osgood File – Ultrasound for Arthritishttp://www.westwood-backup.com/pg/jsp/osgood/transcript.jsp?pid=34091
Teaching
Classroom Instruction
2005-2006
Albany Medical College – Union University. Junior Chief Resident Lectures. Pathophysiology in Internal Medicine, for 3d year medical students.
2010
Columbia University, College of Physician and Surgeons: Pathophysiology course lecturer and instructor for Columbia University Medical Students
2010
Columbia University, College of Physician and Surgeons : Internal Medicine Resident Didactic noon conference lecturer
2010
Columbia University, College of Physician and Surgeons : Physical medicine and Rehabilitation Resident Morning didactic noon conference lecturer
2012
Columbia University, Mailman School of Public Health: MPH student Lecture ( Topic: Epidemiology of Chronic diseases)
2013
Columbia University Medical School, Body in health and disease - Second year medical students pathophysiology, Myositis lecture and small group instruction
 
Clinical Instruction
2005-2006
Albany Medical College – Union University, Junior Chief Resident Clinical Instruction, Medical history and physical examination skills for 3d year medical students.
2006-2009
Johns Hopkins University, Small Group Preceptor for Patient Encounters, "Clinical Skills" - an introduction to history and physical examination for second year medical students. 
2009-2010
Johns Hopkins Arthritis Center: Bedside instruction of residents fellows in Arthritis Center. Teaching of Musculoskeletal Ultrasound to Rheumatology fellows in Rapid Arthritis Care and Evalutaion (RACE) center.
2010
Columbia University, College of Physician and Surgeons : Bedside instruction of residents fellows in Arthritis Center.
2010
Columbia University, College of Physician and Surgeons : Teaching of Musculoskeletal Ultrasound to Rheumatology fellows.
 
CME Instruction
07/21/06
Differential diagnosis of arthritis and rash in the setting of Cystic Fibrosis. Rheumatology Rounds , Division of Rheumatology, Johns Hopkins University
08/04/06
The role of MRI imaging in the evaluation of sacroiliitis. Rheumatology Rounds , Division of Rheumatology, Johns Hopkins University
10/13/06
An Emerging "Great Imitator". Rheumatology Rounds , Division of Rheumatology, Johns Hopkins University
01/19/07
“An Ulcer in the Buttock”. Rheumatology Rounds , Division of Rheumatology, Johns Hopkins University
10/19/07
Glucocorticoid Treatment is Associated with Increased Insulin Resistance in Subjects with Rheumatoid Arthritis. Rheumatology Rounds , Division of Rheumatology, Johns Hopkins University
07/22/10
Rheumatology Preceptorship, Interstitial Lung Disease in Rheumatoid Arthritis, Division of Rheumatology, The Johns Hopkins Hospital, Baltimore, MD.
 
Mentoring
Advisees
2009- 2010
Marzouq Qubti, MD, Post-Doctoral Rheumatology Fellow. ( Role: mentoring in the use of musculoskeletal ultrasound use for diagnostic and interventional purposes in patients with arthritis)
Janet Maynard, MD, Post-Doctoral Rheumatology Fellow. ( Role: mentoring in the use of musculoskeletal ultrasound use for diagnostic and interventional purposes in patients with arthritis)
2009-2010
Anastasia Markopoulou, MD, Post-Doctoral Rheumatology Fellow. ( Role:
  1. mentoring in the use of musculoskeletal ultrasound use for diagnostic and interventional purposes in patients with arthritis)
  2. mentoring in clinical research, epidemiology and biostatistics)
 
CLINICAL ACTIVITES
Certification
Medical, other state/government licensure
2010 – Present
New York# 003727-1
2009 - 2010
Maryland # DOO 68969
 
Boards, other specialty certification
2003
Educational Commission for Foreign Medical Graduates /ECFMG
2006
American Board of Internal Medicine
2009
American Board of Internal Medicine (Rheumatology)
2009
Ultrasound School of North America for Rheumatologists (Musculoskeletal Ultrasound for Rheumatology)
 
Clinical (Service) Responsibilities
2009 – 2010
Johns Hopkins Arthritis Center Clinic
2009 – 2010
Johns Hopkins Rapid Arthritis Care and Evaluation (RACE) center
2009 – 2010
Johns Hopkins Bayview, attending, Rheumatology Consult Service
2010 – 2013
New York Presbyterian Hospital, Arthritis Center Clinic
2010 – 2013
New York Presbyterian Hospital, Fast Arthritis Sonographic Evaluation and Treatment (FAST) center, attending
2010 – present
New York Presbyterian Hospital , Attending, Rheumatology Consult Service
2010 - 2013
New York Presbyterian Hospital, Attending, Internal Medicine Service
 
ORGANIZATIONAL ACTIVITIES
Institutional Administrative Appointments
2010- present
Director, Fast Arthritis Sonographic evaluation and Treatment ( FAST) center, Division of Rheumatology, Department of Medicine, Coilumbia University, College of Physicians and Surgeons.
2009 – 2010
Co-director, Rapid Arthritis Care and Evaluation (RACE) center, Division of Rheumatology, Department of Medicine, Johns Hopkins University.
 
Editorial Activities
Journal peer-review activities, Reviewer
2008 - present
Arthritis and Rheumatism
2008 - present
Arthritis Care and Research
2008 - present
The American Journal of Medicine
2010 - present
US Musculoskeletal Review
2010 - present
Lupus
 
Advisory Committees, Review Groups/Study Sections
2009 - present
Member, OMERACT, Connective Tissue Disease Related Interstitial Lung Disease Special Interest Group (CTD-ILD SIG)
2010 - present
Scientific director – CORRONA CERTAIN study, Consortium of Rheumatology Researchers of North America.
2011 - present
Scientific director – CORRONA International , Consortium of Rheumatology Researchers of North America.
2010 - present
Scientific Advisory Board –Consortium of Rheumatology Researchers of North America (CORRONA).
 
Professional Societies:
2009 – present
Member, American Medical Association
2008 – present
Member, Arthritis Foundation
2006 – present
Member, American College of Rheumatology
2004 – present
Member, American College of Physicians
1999 – present
Member, Greek Medical Association
 
RECOGNITION
Awards, Honors
2002
ACP Poster Finalist, National Associates Clinical Associate Poster Competition
2003
Albany Medical College – Union University Housestaff Research Award.
2004
MARRC Senior Fellowship, Arthritis Foundation, Maryland Chapter
2006
American College of Rheumatology ACR-FIT scholarship
2007
American College of Rheumatology ACR-FIT scholarship
 
Invited Talks, Panels (Only international)
2010
Speaker, RNS national meeting, “Patient reported outcomes”, Chicago, Illinois
2010
Speaker, University of Athens, Joint Training Program on Systemic Rheumatic Diseases , “Respiratory Involvement in Rheumatoid Arthritis”, Athens, Greece
2010
Speaker, Weill Cornell University Grand Rounds, Lincoln Hospital, Rheumatoid Arthritis in the era of biologic agents, New York, NY
2011
Speaker, SPAR Rheumatology Meeting “Rheumatoid Arthritis and Cardiovascular Risk Factors”, Monterey, CA
2011
Panel Member, AHRQ Outcome Initiative: Registries of Patient Registries Washington, DC
2011
Tutor/Instructor, Advanced Course for Musculoskeletal Ultrasound for Rheumatologists, University of Florida, Jacksonville, FL
2012
Panel Member, Consortium of Scientific Researchers of North America Scientific Advisory Board, Chicago, IL
2012
Round Table Discussion for the use of musculoskeletal ultrasound in Rheumatology, American College of Rheumatology national meeting, “Disease Activity Measures”, Washington, DC
2013
Speaker, Novartis Educational Meeting, “Psoriatic Arthritis”, New York, NY
2015
Speaker, Athens Medical Center : CME courses – Rheumatoid Arthritis and Cardiovascular disease
2015 - 2016
Speaker, European Society for Diabetes and Metabolic Syndrome : Rheumatoid Arthritis and Cardiovascular disease
2014
Speaker, National Greek neurology meeting, Rheumatologic diseases in the differential diagnosis of demyelination
2018
Athens Medical Center : CME courses – Spondyloarthropathies